Comorbidities
Asthma, COPD, atopic dermatitis, nasal polyps: different diseases, one shared mechanism
Do you live with a chronic respiratory or skin condition?
Symptoms such as shortness of breath, coughing, a blocked nose, itching and loss of smell can become so familiar that we end up seeing them as 'normal'.
But they are not. You can expect more from your daily life... and it starts with a better understanding of what is happening in your body.
For example, did you know that asthma, COPD, atopic dermatitis and nasal polyps can sometimes be linked? This link is called type 2 inflammation. This process triggers persistent inflammation throughout the body and is responsible for many symptoms that affect the skin, nose and airways.1-3
Type 2 inflammation: a common thread between several conditions
Don't let your symptoms take over your daily life. Watch the video below to discover the link between asthma, COPD, atopic dermatitis and nasal polyps, and to find out how a better understanding of your condition can improve your quality of life.
Did you know?
Some people experience asthma, atopic dermatitis and nasal polyps simultaneously. These conditions are all linked by the same underlying mechanism: type 2 inflammation.
Up to 50% of people with nasal polyps also have asthma.4
15% of people with asthma also have atopic dermatitis.5
Approximately 26% of people with atopic dermatitis also live with asthma.6
People with asthma, COPD, atopic dermatitis or nasal polyps often believe that their condition is 'under control'. In reality, however, this is rarely the case. A few figures illustrate this:
- Among people with severe asthma, 73% believe their condition is well controlled, but only 15% actually are.7
- In COPD, the disease can remain unnoticed for a long time: it is estimated that 2 out of 3 patients are undiagnosed.8
- Atopic dermatitis and nasal polyps can also significantly affect quality of life,9-11 causing sleep disturbances, fatigue, social isolation or anxiety.
Living well with your condition is possible.
It all starts with a better understanding of your health and appropriate follow-up with your doctor.
Is your condition truly under control?
Find out now by taking a quick online test or asking your doctor for advice.
Don't let your symptoms get the better of you.
Type 2 inflammation can be better understood and managed.
Talk to your doctor about how to regain control of your daily life.
- N. A. Gandhi, B. L. Bennett and N. M. Graham, “Targeting key proximal drivers of type 2 inflammation in disease,” Nature Reviews Drug Discovery, vol. 15, no. 1, pp. 35-50, 16 October 2016.
- S. Carr, E. Chan, and W. Watson, “Eosinophilic esophagitis,” Allergy, Asthma & Clinical Immunology, vol. 14, no. Suppl 1, p. 58, 2018.
- J. W. Steinke and J. M. Wilson., “Aspirin-exacerbated respiratory disease: pathophysiological insights and clinical advances.,” Journal of Asthma and Allergy, vol. 9, pp. 37-43, 2016.
- Promsopa C., Kansara S., Citardi MJ., Fakhri S., Porter P., Luong A. Prevalence of confirmed asthma varies in chronic rhinosinusitis subtypes. Int Forum Allergy Rhinol. 2016 Apr;6(4):373-7. doi: 10.1002/alr.21674. Epub 2015 Dec 17. PMID: 26678021; PMCID: PMC4818724.
- Khan AH, et al., Type 2 inflammation-related comorbidities among patients with asthma, chronic rhinosinusitis with nasal polyps, and atopic dermatitis, presented at the European Respiratory Society International Congress 2020; 7-9 September 2020, DOI: 10.1007/s00408-023-00603-z.
- Jacob P. et al., Comorbidities of atopic dermatitis—what does the evidence say?, Journal of Allergy and Clinical Immunology, Volume 151, Issue 5, 2023, Pages 1155-1162, ISSN 0091-6749, https://doi.org/10.1016/j.jaci.2022.12.002.
- Molimard M., Vervloet D., Le Gros V., Bourdeix I., Ponthieux A. Insights into severe asthma control as assessed by guidelines, pulmonologist, patient, and partner. Journal of Asthma. oct 2010;47(8):853 9.
- Santé Respiratoire France. La broncho-pneumopathie chronique obstructive (BPCO) et l’emphysème. https://sante-respiratoire.com/les-maladiesrespiratoires/bpco/. Page accessed in November 2025.
- T. Zuberbier , S. Orlow and A. Paller, “Patient perspectives on the management of atopic dermatitis,” Journal of Allergy and Clinical Immunology, vol. 118, no. 1, pp. 226-232, 2006
- L. Rudmik and Z. Soler, “Medical Therapies for Adult Chronic Sinusitis: A Systematic Review,” JAMA Dermatology, vol. 314, no. 9, pp. 926-939, 2015.
- C. Rand, R. Wright and M. Cabana, “Mediators of asthma outcomes,” J Allergy Clin Immunol, vol. 129, no. 301, pp. 136-141, 2012.
MAT-BE-2501441 v1.0 | 11/2025